Dichloroacetate
Dichloroacetate (DCA) is a new cancer treatment used alongside other therapies. It’s often recommended when using a metabolic strategy to fight the cancer.
HOW IT WORKS
Understanding DCA Therapy
What is DCA Therapy?
In 1931, Otto Warburg, a German physician, won the Nobel Prize for his research in cancer physiology and metabolism. His research outlined the unique metabolic properties of cancer cells compared to normal cells. Later, this mechanism was described as the Warburg Effect.
DCA is a water-soluble compound administered orally or intravenously and leverages these differences to affect cancer cells and the tumour microenvironment (TME).
How DCA Therapy Works
DCA acts as a pyruvate dehydrogenase kinase (PDK) inhibitor, disrupting the metabolic advantage of cancer cells. In turn, it improves mitochondrial function and reduces cancer cell viability.
Our Approach
Our clinic offers access to discussions on integrative modalities, such as DCA. When appropriate, these therapies may be explored in collaboration with each patient’s care team.
We do not claim DCA is a treatment or cure for any disease. Instead, our role is to educate, inform, and support patients seeking to understand the range of integrative approaches being studied internationally and used in integrative settings to best achieve their health goals.
FAQs
Frequently Asked Questions
Many patients are curious about Dichloroacetate Therapy as an integrative option to their care. Explore the top five most asked questions.
Is Dichloroacetate (DCA) safe?
When used under medical supervision, DCA therapy is generally well-tolerated with little to no side effects.
What are the possible side effects?
Side effects are rare, but the most common is reversible peripheral neuropathy. Clinicians often use antioxidants such as alpha-lipoic acid (ALA) in conjunction with DCA to mitigate these side effects.
Is there scientific literature pertaining to DCA?
Yes, DCA has been studied both in vitro and in human pre-clinical and randomized control trials.
How long does a DCA infusion take?
Typical sessions last 60-120 minutes.
Can it be combined with other therapies?
Yes. DCA is often used in integrative settings alongside conventional and integrative oncology therapies such as chemotherapy and ALA. Supervision by a qualified healthcare professional is recommended, as interactions with other therapies may occur.
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